About LipiGesic M

For FAST relief, begin treatment at first sign of migraine headache pain

LipiGesic M is a homeopathic product containing Feverfew 3X and Ginger 2X, formulated to provide acute migraine headache relief. It has been used successfully to treat migraines, hangover symptoms, and menstrual headaches and certain other types of headaches. LipiGesic M is more effective when taken early on in the course of a headache, though it can be used at any point. Most users have reported excellent results even when the headache is well underway.

LipiGesic M’s patent-pending formulation uses the sublingual delivery of the natural ingredients of feverfew and ginger to stop migraine headache.

Unlike oral tablets, LipiGesic M uses sublingual (under-the-tongue) delivery for the fast absorption of more of the active ingredients, feverfew and ginger, into the blood stream. The result for most migraine sufferers is relief in minutes, not hours, not days.

LipiGesic M has a superior safety profile, and no known drug interactions. By administering Feverfew 3X and Ginger 2X under-the-tongue, this migraine treatment provides acute migraine pain relief.

LipiGesic M is safe. There are no major side effects associated with this over-the-counter migraine medication when used as directed.

LipiGesic M is a sublingual formulation that speeds the homeopathic ingredients into the blood stream. Administered under the tongue, the gel is absorbed quickly — providing fast relief from migraine pain.

The pre-measured dose is convenient to carry and easy to use. Directions for use.

  • Open one unit dose dispenser by tearing off the perforated end and dispensing entire contents under the tongue.
  • Important: Hold in place under the tongue for at least 60 seconds, then swallow.
  • Repeat after 5 minutes using a second unit dose dispenser, making certain to hold the second dose under the tongue for at least 60 seconds before swallowing.
  • Additional medication may be taken after 30 minutes, either 1 or 2 unit dose dispensers, as needed or as directed by doctor.

Why LipiGesic M is a fast and effective migraine treatment

Feverfew 3X (Pyrethrum Parthenium)

Feverfew 3X the main active ingredient in LipiGesic® M, is an herb that has been recognized for centuries as having a beneficial effect on migraine, menstrual and other headaches. The last two decades have seen a sustained and increasing interest in Feverfew as a daily prophylactic (preventative) treatment for migraine.

Several studies published in leading medical journals, including “Lancet”, and “The British Medical Journal”, have demonstrated Feverfew potential for reducing the incidence and severity of migraines. Patients reported a reduction in the number and/or severity of migraine attacks, with no significant side effects reported by either study.

More recent studies have shown that Feverfew 3X when combined with Ginger 2X is an effective treatment to decrease or prevent migraine pain when used at the onset of a headache.

Sublingual (under-the-tongue) delivery avoids active ingredient breakdown

In the past, feverfew tablets sold in the U.S. were found to have very little, if any, active ingredient. Whatever active ingredient was in the tablets was broken down during digestion by the stomach and liver; this diminished feverfew’s effectiveness. The low concentration of active ingredient in many feverfew tablets and its very slow onset of action have led most to conclude that feverfew is not a very effective treatment for migraines. That perception is wrong. While feverfew tablets are not very effective; feverfew itself is extremely effective.

How Feverfew prevents or reduces migraine pain without rebound headache

Feverfew acts to inhibit over-aggregation of platelets, thought to be a part of the migraine ‘cascade’. During a migraine attack, these platelets release serotonin, which causes abnormal blood vessel tone, and can result in both their dilation and constriction (both of which are believed to contribute to migraine attacks). Inflammatory substances are released locally, which then contribute to the severity of the attack. Feverfew blocks the production of these inflammatory substances and short-circuits the migraine cascade.

The net result is a normalization of blood vessel tone. Feverfew does not constrict blood vessels like most prescription migraine drugs (e.g. triptans such as sumatriptan – “Imitrex”). Blood vessel constriction is associated with an increased risk of heart attack during the use of these vasoconstrictors, and is one reason why Imitrex is not appropriate for a large percent of the population.

Vasoconstriction is also associated with the occurrence of rebound headaches (when so much of a non-steroidal is taken that a headache ensues when the patient stops taking them).

Ginger 2X (Zingiber)

Ginger has also been shown to be anti-inflammatory, specifically suppressing the expression of several mediators felt crucial in migraine pathogenesis. In studies, Ginger is shown to suppress the pro-inflammatory compounds (cytokines and chemokines) produced by synoviocytes (cells comprising the synovial lining of the joints), chrondrocytes (cells comprising joint cartilage) and leukocytes (immune cells).

LipiGesic M’s unique and proprietary formulation of Feverfew 3X and Ginger 2X is manufactured for PuraMed BioScience, Inc. It is manufactured according to the highest standards to ensure product quality and consistency.

Keep this and all drugs out of the reach of children.