SCHOFIELD, Wis., April 24, 2012 /PRNewswire/ – PuraMed BioScience, Inc. ^® (OTC Bulletin Board: PMBS), the producer of over-the-counter medicinal and healthcare products, has implemented an aggressive public awareness campaign to promote LipiGesic M in the retail sector with major campaigns planned in May and June to promote sales at both Walgreens and CVS/pharmacy stores.

LipiGesic M is a unique, homeopathic formulation of feverfew and ginger that is delivered sublingually (under the tongue). This method of delivery allows the absorption of full-strength active ingredients directly into the bloodstream for effective and fast results. Many users report feelings of relief within minutes of taking the medication.

“We are ramping up flights of our radio endorsement and placements of newspaper advertisements to target key metropolitan areas to create awareness of LipiGesic M and expand retail sales,” says PuraMed BioScience CEO Russell Mitchell. “We have implemented a manufacturer’s coupon campaign as an added incentive for migraine sufferers to try LipiGesic M as affordable and effective relief from migraine.”

PuraMed BioScience has also invested in efforts to build the awareness of: pharmacists through advertisements placed in Pharmacy Times magazine; health care providers by attendance at key medical conferences, including National Headache Foundation events; headache specialists and headache sufferers through advertisements placed in Headwise magazine; and the general public through expert interviews featured on local news programs in key markets around the country.

A team of third-party experts has also supported LipiGesic M in various media venues. Medical researcher and headache expert, Roger Cady, MD, mentioned LipiGesic in an article by Fox News http://www.foxnews.com/health/2012/04/11/5-natural-headache-remedies/. LipiGesic M also has endorsements from holistic pharmacist, author and lecturer, Sherry Torkos, B.Sc, Phm; and fitness and nutrition expert, J. J. Virgin. These efforts along with presence on social media channels are designed to support the retail expansion of LipiGesic M.

“We are pleased with the response that we have received from the medical community,” says Mitchell. “We look forward to letting the public know that there is a clinically-tested, over-the-counter medication that is an effective and affordable treatment for migraine.”

In a clinical study conducted by leading headache researcher Dr. Roger Cady, LipiGesic M was shown to reduce or eliminate migraine pain in 63 percent of occurrences at two hours post dose. The findings of this clinical trial were published in the July 2011 issue of Headache: The Journal of Head and Face Pain, a top-tier medical journal of the American Headache Society*. The study also concluded that LipiGesic M’s proprietary formula of feverfew and ginger appears to be a safe and effective first-line treatment when taken at the onset of migraine.

For additional information on LipiGesic M, visit www.LipiGesicM.com.

*Cady RK, Goldstein J, Nett R, et al. A Double-Blind Placebo-Controlled Pilot study of (LipiGesic® M) Sublingual Feverfew and Ginger in the Treatment of Migraine. Headache: The Journal of Head and Face Pain. 2011; 51:1078-1086

About PuraMed BioScience, Inc.^®:

PuraMed BioScience, Inc. ^®  engages in the research, development and marketing of non-prescription medicinal and healthcare products. In addition to its leading product LipiGesic^® M, which provides acute relief from migraine headaches. PuraMed BioScience also has plans to launch LipiGesic™ PM that provides a remedy for insomnia and other sleep disorders as well as LipiGesic™ H for tension-type headaches. For more information on PuraMed, visit the Company website at www.PuraMedBioScience.com, join the Company’s group page on Facebook by searching “PuraMed BioScience” and follow the Company on Twitter at www.twitter.com/puramed.

Forward Looking Statements:

This news release contains forward-looking statements regarding PuraMed BioScience and its future business plans, which statements involve known and unknown risks and uncertainties. Such risks and uncertainties may cause actual results and future achievements of PuraMed BioScience to be materially different than those implied by these forward-looking statements. PuraMed BioScience has and undertakes no obligation to provide public updates and revisions to these forward-looking statements to reflect any changes in its expectations of future events.

For more information, contact:

Russell Mitchell, Chairman and CEO
PuraMed BioScience, Inc.
715-359-6373
rmitchell@PuramedBioScience.com
Website: www.PuramedBioScience.com

I have to tell you that I have not had the chance to try the migraine relief myself (which is good, no headache!) but, on Easter my 12-year-old granddaughter had a terrible headache after being outside playing softball and egg hunting.

She was laying down, crying a little and told me that it hurt in her right eye/eyebrow area.  I gave her the one dose, she held it under her tongue for a minute, and then took the second dose 5 minutes later.  With no complaints about taste or anything.  She said she felt a little better and came back out for dessert (we were celebrating her 12th birthday as well as Easter).

We sang happy birthday, and were sitting talking, when she turned to me and said “that stuff worked! My head feels completely better!”

Thanks so much for introducing me to this, I am going to have to go to Walgreens this weekend to see if I can stock up on some.

Kathy

Are Migraines Hereditary?

Yes, migraines have a tendency to run in families. Four out of five migraine sufferers have a family history of migraines. If one parent has a history of migraines, the child has a 50% chance of developing migraines, and if both parents have a history of migraines, the risk jumps to 75%.

You can reduce the frequency of your migraine attacks by identifying and then avoiding migraine triggers. While it varies for each person, common triggers include stress, certain foods, hormones and yes, even many pain medications may CAUSE headaches known as rebound headaches.

Some Pain Medications Actually Cause Headaches

Many commonly used pain relief medications, when taken in large enough amounts, can cause rebound headaches. Drugs once thought of as “safe” are turning up as the likeliest culprits. These include:

• Aspirin
• Sinus relief medications
• Acetaminophen (Tylenol)
• Non-steroidal anti-inflammatory medications (Aleve)
• Sedatives for sleep
• Codeine and prescription narcotics
• Over-the-counter combination headache remedies containing caffeine (such as Anacin, Excedrin, Bayer Select)
• Ergotamine preparations (such as Cafergot, Migergot, Ergomar, Bellergal-S, Bel-Phen-Ergot S, Phenerbel-S, Ercaf, Wigraine, and Cafatine PB)
• Butalbital combination pain-relievers (Goody’s Headache Powder, Supac, Excedrin)

While small amounts of these drugs per week may be safe (and effective) — at some point, the continued medication use can lead to the development of low grade headaches that just will not go away.

LipiGesic M is a different type of migraine treatment.

Unlike many of these medications, LipiGesic M does not contain the ingredients that cause headaches. It’s ingredients are all natural – feverfew and ginger – which help to reduce both the inflammation and the nausea often associated with migraine pain. And because it is administered under the tongue, it is absorbed directly into the blood stream, so it goes to work fast.

It started during my teenage years.  I was devastated because I did not know where the pain was coming from.  My mother took me to the eye doctor because the pain was making me squint. The eye doctor said my eyes were fine but the squinting and headaches may be from eye strain when reading, so I was prescribed glasses to wear for reading.  Of course it did not help.  I remember getting a bad migraine in my Math class and my teacher suggested that I massage my temples to relieve the pain.

Most often I would receive relief (but not total) from taking aspirin or Tylenol®, curl up in my bed with dark or silence. Over time, the migraine would ease to the point that I could function. Then my sister, Karen, started to complain about the same thing. She also was prescribed glasses but her pain did not stop either.

Finally our family doctor diagnosed that we had migraines that were triggered by different situations and foods one of which was pork. Both of us stopped eating pork which seemed to help greatly but once we became adults the migraines came back with menstrual cycles and stressful situations.

Once again to cope with it, I would take aspirin or ibuprofen 800 mg, drink water and lay down in a quite room. This was annoying. I am the mother of two boys; I home school my kids; and I am a business owner. Needless to say, the migraines would take up my day.

My sister, Karen, would rotate between Aleve® and Tylenol and Excedrin Migraine®. None of which took it completely away.

We discussed neurology and other ways to find a cure since the migraines were mainly during our menstrual cycles and stressful situations. Neither of us wanted to continue with the distraction and discomfort especially with kids and busy entrepreneurial lifestyles. We both preferred natural alternatives but did not know of any specifically.

When LipiGesic® M was introduced to me last summer, I was happy to try it.  I was excited about this natural alternative. I first tried it during one of my menstrual cycle episodes. I was so amazed to feel the pressure across my temple ease up with just one dose — literally within the first minute. It is truly wonderful; so I told my sister, Karen.  She too had great results with the first dose.

In December my sister, Denise, complained to me about getting a bad migraine all of a sudden. She said they had been bothering her off and on for weeks. Migraines had become so bothersome they were causing her to seek medical attention. I asked her what she was taking. She said ibuprofen and Tylenol but the migraines would ease up and after a while they would come back. I immediately told her about LipiGesic M and had samples shipped to her.

Once again, great results! She said she took it once and it went away and has not returned since. She even gave it to my 14-year-old niece and she had the same result. The migraine did not return! This is a great reliable product. I will continue to recommend LipiGesic M because the results change lives!!!

Kathy B., Ft. Lauderdale, FL.

Dear JJ,

Thank you for your Migraine suggestion!! This morning LipiGesic M stopped my migraine in mid pattern on the way to a tennis match.

I am a 55 year old very competitive (present points leader 55s in CA) tennis player who has suffered with reoccurring migraines since my twenties.

I have tried many medicines and remedies over the years with little or no relief. My symptoms are so predictable and patterned (disjointed feelings, finger numbness, peripheral sight loss, followed by debilitating headaches and increased sensory acuity).

Until now, once the pattern started my only option had been drink coffee, take aspirin, and wait for it to run its painful course.

You suggested LipiGesic M and I put some in my touring tennis bag. On my way to an important match this morning my migraine reared its ugly head and simple driving started to become difficult. I pulled over to find my NSAIDs in my tennis bag and found the LipiGesic M.

It’s a little weird to take, placed under the tongue and held for 60 seconds then swallowed, but within moments my vision was restored, and rather than call and default, I played and won. By the time I reached the match site I was normal. Amazing! No headache at all! For the first time in 30 years, I have something that stops my migraine in its tracks instead of it stopping me.

Thank You JJ Virgin!

Very truly yours,
John V

Dear JJ,

Thank you for your Migraine suggestion!! This morning LipiGesic M stopped my migraine in mid pattern on the way to a tennis match.

I am a 55 year old very competitive (present points leader 55s in CA) tennis player who has suffered with reoccurring migraines since my twenties.

I have tried many medicines and remedies over the years with little or no relief. My symptoms are so predictable and patterned (disjointed feelings, finger numbness, peripheral sight loss, followed by debilitating headaches and increased sensory acuity).

Until now, once the pattern started my only option had been drink coffee, take aspirin, and wait for it to run its painful course.

You suggested LipiGesic M and I put some in my touring tennis bag. On my way to an important match this morning my migraine reared its ugly head and simple driving started to become difficult. I pulled over to find my NSAIDs in my tennis bag and found the LipiGesic M.

It’s a little weird to take, placed under the tongue and held for 60 seconds then swallowed, but within moments my vision was restored, and rather than call and default, I played and won. By the time I reached the match site I was normal. Amazing! No headache at all! For the first time in 30 years, I have something that stops my migraine in its tracks instead of it stopping me.

Thank You JJ Virgin!

Very truly yours,
John V

The recent recall of Excedrin Migraine by Swiss drug company Novartis has left store shelves empty and many people without the over-the-counter medicine they typically used to treat their migraines.

Many migraine sufferers may feel that the only alternative they have is to go to the doctor for a migraine diagnosis and pay, not only for the doctor visit, but sometimes as much as 75 percent more for prescription medications prescribed to stop migraine headache.

But there is a NEW migraine relief product on the shelves at Walgreens, CVS/pharmacy and available online that is not only more effective for many migraine sufferers, but also costs a lot less. It’s called LipiGesic® M.

LipiGesic M is an all-natural, non-prescription formulation that relieves migraine pain and its associated symptoms in 64 percent of occurrences.

LipiGesic M is noticeably different from the start. Pills and other medications absorbed through the digestive tract generally take up to an hour just to start working, and absorption is highly variable. LipiGesic M is a gel that is applied under the tongue, which means that absorption into the bloodstream starts … and begins working … within minutes.

LipiGesic M’s active ingredients, feverfew and ginger, have had a long history of use. These two natural ingredients have been combined to provide a unique and powerful defense against migraine pain and its associated symptoms. This formulation does not cause severe side effects and there are no known drug interactions. In addition, Ginger has long been known to reduce nausea, a symptom often associated with migraine headaches.

LipiGesic M is non-habit forming, and unlike many over-the-counter migraine remedies, it does not cause rebound headaches. It can be taken repeatedly and is still effective.

You don’t need a doctor’s order. LipiGesic M is safe, fast, and effective for reducing or eliminating migraine pain and associated symptoms.

Did you know that nine out of ten sinus headaches are really undiagnosed migraines?

While the incidence of sinus headaches is large, 37 million each year, according to the American Academy of Otolaryngology – Head and Neck Surgery, they are usually accompanied by fever, swollen lymph nodes and nasal discharge.

Confusing sinus headache with migraine is common. Having had a sinus headache before, feeling the same type of pain may cause people to assume a sinus headache.

According to Roger Cady, MD, director of the Headache Care Center in Springfield, Missouri, most self-diagnosed sinus headaches are actually migraine. While both types of headaches have symptoms of pain in the forehead and around the eye, a sinus headache will be associated with pus-like [green or yellow] nasal discharge.

Migraines may also cause watery eyes, a runny nose with clear fluids and debilitating pain.*

The finding of the an investigation done at the Mayo Clinic in Scottsdale, Arizona confirmed that 90 out of the 100 volunteers who thought they had sinus headache were really suffering from migraine headache.

Even when headache pain becomes unbearable, there is the potential for misdiagnosis. The study completed by the Mayo Clinic investigated the headache symptoms of 100 volunteers who had visited as many as four health care providers at some point for headache pain:

64% of them saw their family doctor
59% saw an Ear, Nose and Throat (ENT) specialist
25% of them saw an allergist
19% saw a neurologist.

Among those that saw the neurologist, 83% got a correct migraine diagnoses. Among those who saw ENT’s got a 8.1% migraine diagnoses. Only 6.3% got a migraine diagnoses from an allergist.

The cost of misdiagnosis. For many people, having a headache is a way of life – not a reason to go to the doctor. That may be why many people self-diagnose and treat their headache with over-the-counter medications.

But this can be expensive and ineffective. Medications to treat sinus and tension headaches rarely work in the treatment of migraine. When the headache pain becomes intolerable, people are likely to miss work, school or special events in their lives.

Neurologist, Richard Lipton, MD, and a research team at Albert Einstein University formulated a three-question self-assessment called ID Migraine to diagnose a possible migraine.

1. Has headache limited your activities for a day or more in the last three months?
YES / NO

2. Are you nauseated or sick to your stomach when you have a headache?
YES / NO

3. Does light bother you when you have a headache?
YES / NO

If you answered “YES” to any 2 of these questions you may be suffering migraine and should contact your local headache specialist.

Thank you what a blessing. I have suffered with bad headaches that would last for days.
I have tried every product you can buy without a prescription, nothing worked.
I printed the LipiGesic M coupon and decided it was time to try something new. My headache was gone in under 30 minutes. Thank you again.

S. Smith

Migraine suffers know that stress can be a trigger for migraine headaches.  Since most life situations that cause stress are extremely important, it is a challenge for people who suffer recurrent migraines to continue to function at peak performance during those crucial moments in their lives.

Many prescription medications in today’s marketplace have side effects that can be almost as debilitating as the headache itself, which can also cause people to miss events.

But now there is an over-the-counter migraine medication that works in 64 percent of migraine occurrences … with no severe side effects, so that people can get on with the important events in their lives.

At PuraMed BioScience, we love to hear how our product LipiGesic M changes people’s lives! It is the motivation that has made us … and keeps us … passionate about our product.

Recently, we received the following testimonial from a gentleman who was recommended LipiGesic M by JJ Virgin a nutrition & fitness expert. His letter is below.

Dear JJ,

Thank you for your Migraine suggestion!! This morning LipiGesic M stopped my migraine in mid pattern on the way to a tennis match.

I am a 55 year old very competitive (present points leader 55s in CA) tennis player who has suffered with reoccurring migraines since my twenties.

I have tried many medicines and remedies over the years with little or no relief. My symptoms are so predictable and patterned (disjointed feelings, finger numbness, peripheral sight loss, followed by debilitating headaches and increased sensory acuity).

Until now, once the pattern started my only option had been drink coffee, take aspirin, and wait for it to run its painful course.

You suggested LipiGesic M and I put some in my touring tennis bag. On my way to an important match this morning my migraine reared its ugly head and simple driving started to become difficult. I pulled over to find my NSAIDs in my tennis bag and found the LipiGesic M.

It’s a little weird to take, placed under the tongue and held for 60 seconds then swallowed, but within moments my vision was restored, and rather than call and default, I played and won. By the time I reached the match site I was normal. Amazing! No headache at all! For the first time in 30 years, I have something that stops my migraine in its tracks instead of it stopping me.

Thank You JJ Virgin!

Very truly yours,
John V

Letters like John V’s are why we are so passionate about our product and passionate about getting it into the hands of people all over the country.

You can find LipiGesic M at your local Walgreens and CVS/pharmacy stores. If you can’t find it on the shelves, please ask your pharmacist if they will be getting more soon. If you want to order your supply right away, you can order online at Walgreens.

You can also download a coupon at http://www.lipigesic.com/save/.

Please let us know how our product works for you.